With the pod system, getting screwed doesn't always have to do with the seeding either. The NCAA always says they will give special consideration for teams that have been forced to travel in past years.....
2012: @ Louisville
2011: @ Cleveland - could have been in Chicago, but VCU got that seed.
2010: @San Jose
2009: @Boise
2008: @Anaheim
2007: @Winston-Salem
2006: @San Diego
Yep, that is a good stretch of special consideration there.